Subluxation and Dislocation of the Lens (Ectopia Lentis)

Subluxation and Dislocation of the Lens Subluxation or dislocation of the lens, also called ectopia lentis , refers to a partial or complete displacement of the crystalline lens from its normal position due to the weakening or rupture of zonular fibers. Subluxation : The lens is partially displaced but remains within the pupillary area. Dislocation (Luxation) : The lens is completely displaced out of the pupillary area, either into the anterior chamber or the vitreous cavity. Causes of Lens Subluxation/Dislocation A. Traumatic Causes Blunt trauma (e.g., sports injury, road traffic accident) Penetrating trauma (e.g., sharp object injury, gunshot wounds) B. Non-Traumatic Causes 1. Congenital/Hereditary Causes Marfan syndrome - Lens subluxation is usually superotemporal . Homocystinuria - Lens dislocation is inferonasal . Ehlers-Danlos syndrome - Can cause lens instability. Weill-Marchesani syndrome - Lens dislocation often inferior . 2. Acquired Causes Pseudophakia (complication of cataract surgery) High myo…